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Study highlights: • 153 adults with TRD • Comparison of repeated IV racemic ketamine versus intranasal esketamine • Both treatment groups demonstrated clinically meaningful reductions in depression severity • IV ketamine achieved a 49.2% reduction in depression severity versus 39.6% with intranasal esketamine • Patients receiving IV ketamine experienced more rapid symptom improvement while maintaining a safety profile consistent with previous studies
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Glucagon-like Peptide-1 Receptor Dependent Signaling in Cardiovascular Health and Disease: A Mini-review
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